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Annular elastolytic giant cell granuloma

Identifieur interne : 003889 ( Main/Exploration ); précédent : 003888; suivant : 003890

Annular elastolytic giant cell granuloma

Auteurs : C. William Hanke [États-Unis] ; Philip L. Bailin [États-Unis] ; Henry H. Roenigk Jr. [États-Unis]

Source :

RBID : ISTEX:D793FCFC68F0BDD3D61E7065F6770C38DB5C67A8

English descriptors

Abstract

Five patients with annular lesions of the face, scalp, and other exposed surfaces were studied using the radial triple zone biopsy technic. Interestingly, one of the patients had necrobiosis lipoidica diabeticorum (NLD) and another had systemic sarcoidosis. Clinically, the lesions were annular patches with erythematous borders and hypopigmented centers. The histopathology of the lesions showed many multinucleated giant cells (often with prominent asteroid bodies), histiocytes, lymphocytes, scattered epithelioid cells, total lysis of elastic tissue, no necrobiosis, and absence of both mucin and lipid. This entity can be differentiated from granuloma annulare (GA), NLD, and cutaneous sarcoidosis. It is identical with several previously described entities; we propose a more appropriate term; “annular elastolytic giant cell granuloma (AEGCG).”

Url:
DOI: 10.1016/S0190-9622(79)70033-8


Affiliations:


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Le document en format XML

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<term>Actinic</term>
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<term>Aegcg</term>
<term>Altman</term>
<term>American academy</term>
<term>Annular</term>
<term>Annular elastolytic giant cell granuloma</term>
<term>Annular granulomas</term>
<term>Annular patch</term>
<term>Annular patches</term>
<term>Arch dermatol</term>
<term>Asteroid</term>
<term>Asteroid bodies</term>
<term>Biopsy</term>
<term>Central portion</term>
<term>Cleveland clinic</term>
<term>Cutaneous</term>
<term>Cutaneous sarcoidosis</term>
<term>Dermatol</term>
<term>Dermatology</term>
<term>Dermis</term>
<term>Diabetes mellitus</term>
<term>Diabeticorum</term>
<term>Elastic material</term>
<term>Elastic stain</term>
<term>Elastic tissue</term>
<term>Epithelioid</term>
<term>Epithelioid cells</term>
<term>Erythematous</term>
<term>Forehead lesion</term>
<term>Giant cell granuloma</term>
<term>Giant cells</term>
<term>Glucose tolerance test</term>
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<term>Granuloma annulare</term>
<term>Granuloma multiforme</term>
<term>Granulomatous</term>
<term>Granulomatous inflammation</term>
<term>Histologic</term>
<term>Hydroxychloroquine sulfate</term>
<term>Inflammation</term>
<term>Intralesional triamcinolone acetonide injections</term>
<term>Laboratory studies</term>
<term>Lesion</term>
<term>Lipoidica</term>
<term>Many multinucleated giant cells</term>
<term>Mehregan</term>
<term>Multinucleated</term>
<term>Multinucleated giant cells</term>
<term>Necrobiosis</term>
<term>Necrobiosis lipoidica</term>
<term>Necrobiosis lipoidica diabeticorum</term>
<term>Normal limits</term>
<term>Sarcoidosis</term>
<term>Similar cases</term>
<term>Similar lesions</term>
<term>Skin lesions</term>
<term>Solar elastosis</term>
<term>Systemic sarcoidosis</term>
<term>Term granuloma</term>
<term>Upper dermis</term>
<term>White woman</term>
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<div type="abstract">Five patients with annular lesions of the face, scalp, and other exposed surfaces were studied using the radial triple zone biopsy technic. Interestingly, one of the patients had necrobiosis lipoidica diabeticorum (NLD) and another had systemic sarcoidosis. Clinically, the lesions were annular patches with erythematous borders and hypopigmented centers. The histopathology of the lesions showed many multinucleated giant cells (often with prominent asteroid bodies), histiocytes, lymphocytes, scattered epithelioid cells, total lysis of elastic tissue, no necrobiosis, and absence of both mucin and lipid. This entity can be differentiated from granuloma annulare (GA), NLD, and cutaneous sarcoidosis. It is identical with several previously described entities; we propose a more appropriate term; “annular elastolytic giant cell granuloma (AEGCG).”</div>
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